Effects of Iotensin premedication on sympathetic responses and plasma catecholamine concentration in cervical plexus block
- VernacularTitle:术前口服苯那普利对颈丛阻滞循环副反应和血浆儿茶酚胺浓度的影响
- Author:
Yanxia LU
;
Shuming WEI
;
Zhishuang LIU
- Publication Type:Journal Article
- Keywords:
Lontinsin Cervical plexus block Cardiovascular system Adverse effects Catecholamines
- From:
Chinese Journal of Anesthesiology
1996;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate the effects of lotensin on sympathetic responses following cervical plexus block and to explore the mechanism of cardiovascular responses and sympathetic nervous system activity according to plasma catecholamine concentration. Method: Sixty adult patients were randomly divided into two groups (n = 30):Group A and group B. In group B lotensin 0.15mg/kg was taken orally at night before surgery and 2h before anesthesia separately. Hemodynamics was determined before anesthesia(T_1), 5min(T_2), 10min(T_3), 15-20min(T_4)and 30min (T_5) after cervical plexus block. For measurement of plasma catecholamine concentration, blood was collected at T_1,T_3,T_4 and T_5. The study was finished before beginning of surgery and infusion. Result: In group A after anesthesia SP,DP, MAP,HR,RPP and plasma noradrenalinc level rose markedly(P0.05). All parameters were lower in group B compared with group A(P
