Effect of hypotension induced with metoprolol and nitroglycerin on the blood gas and hemodynamics
- VernacularTitle:美托洛尔复合硝酸甘油与单纯硝酸甘油降压效果比较
- Author:
Congxia LIU
;
Qingyuan ZOU
;
Lei YU
- Publication Type:Journal Article
- Keywords:
Metoprolol Nitroglycerin Hypotension, controlled Blood gas Hemodynamics
- From:
Chinese Journal of Anesthesiology
1996;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
To observe the effect of hypotension induced by metoprolol and nitroglycerin (NTG) on the blood gas and hemodynamics. Method: 36 patients were randomly assigned to two groups. Group Ⅰ with intravenous metoprolol and nitroglycerin infusion (n=18), group Ⅱ with intravenous nitroglycerin infusion (n=18), Result: As compared with those in group Ⅱ, in group Ⅰ NTG dosage decreased by 55.7%. The reflex heart rate augmentation was suppressed, after the discontinuance of drug, the blood pressure increased steadily, rate-pressure prod uct value dereased and hemodynamics was stable. The changes in PaO_2 and BE was significantly lower in group Ⅰ than those in group Ⅱ (P