Propofol eliminates the protective effect of heart pacing-induced preconditioning on the isolated ischemic myocardium
- VernacularTitle:异丙酚消除快速起搏预适应对离体缺血心肌的保护作用
- Author:
Weike MAO
;
Shiying YUAN
;
Shanglong YAO
- Publication Type:Journal Article
- Keywords:
Propofol Preconditioning Myocardial reperfusion injury
- From:
Chinese Journal of Anesthesiology
1996;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
To study the effect of propofol on the protection of ischemic isolated heart preconditioned by rapid heart pacing. Method: 24 white rabbits were assigned randomly into ischemia control (IC), pacing+ischemia (PI), and propofol+pacing+ischemia (PPI)group. Result: After 30 min of total heart isehemia followed by 30 min reperfusion, the recovery level of LVDP, LV+dp/dt max and LV-dp/dt max is much better in PI group than that of IC group (P
