Study on the Expression of Endothelin 1 mRNA in Keratinocytes in Patients with Vitiligo
- VernacularTitle:白癜风角朊细胞内皮素1mRNA表达的研究
- Author:
Jianmin CHANG
;
Tiejun ZHU
;
Shengqing MA
- Publication Type:Journal Article
- Keywords:
Vitiligo Keratinocytes Endothelins
- From:
Chinese Journal of Dermatology
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression of endothelin 1 (ET 1) mRNA in keratinocytes in patients with vitiligo. Methods Fourteen patients with progressive vitiligo were measured by hybridization in situ. Results Our results showed that the expression of ET 1 mRNA was markedly decreased. Conclusion The results revealed that decreased ET 1 expression may be associated with the pathogenesis of vitiligo. The cause and role of decreasing of ET 1 expression of keratinocyte in vitiligo lesion need to be studied further.
