Responses of hemodynamic and electroencephalograph variables to intubation during induction with propofol or propofol-fentanyl
- VernacularTitle:异丙酚或异丙酚复合芬太尼麻醉诱导时病人血液动力学及脑电参数的变化
- Author:
Weidong MI
;
Hong ZHANG
- Publication Type:Journal Article
- Keywords:
Intubation intratracheal Hemodynamics Propofol Fentanyl Bispectral index
- From:
Chinese Journal of Anesthesiology
1996;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe changes of EEG parameters,including bispectral index (BIS),spectral edge frequency(SEF)and median frequency(MF),and the association between the changes of EEG variables and hemodynamic responses to intubation during induction by propofol with or without fentanyl. Method: Twenty-four ASA grade Ⅰ-Ⅱ patients were randomly assigned to double-blindly receiving intravenous propofol/normal saline (group P, n=12)or propofol/fentanyl 2?g/kg(group PF,n=12), respectively. Intubation was performed following 5-min maintenance of BIS within 45?5. EEG and hemodynamic variables were recorded at endpoints of pre-induction, pre-intubation and post-intubation. Result:In group P,blood pressure and heart rate at post-intubation were significantly increased compared with pre-induction value(P
