Study on the Development of Hearing of the Mouse
- VernacularTitle:小鼠听力发育学的研究
- Author:
Yulin ZHAO
;
Mingmin DONG
;
Minsheng DONG
- Publication Type:Journal Article
- Keywords:
Hearing Development Mouse
- From:
Journal of Audiology and Speech Pathology
1998;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
The development of hearing of Kunming strain mouse was studied using evoked auditory nerve action potential (AP). The result showed that the onset of hearing was present during P10( tenth postnatal day) to P14. The thresholds of AP - N1 wave declined gradualy with the growth of the mouse. The auditory thresholds declined dramatically in the period from P10 to P20 and it indicated that the development of hearing was more rapid in this period. The thresholds, amplitudes and latencies of AP - N1 wave attained adult values by P40. The result showed that it took about one month for Kunming strain mouse to attain hearing maturation. The study on the development of hearing in normal mouse may serve as an important reference when studying degenerative lesions of the inner ear and the regeneration of cochlear hair cells.
