Inhalation of nitric oxide combined with intravenous phenylephrine for improvement of arterial hypoxenua in patient with tetralogy of Fallot:a clinical observation
- VernacularTitle:应用一氧化氮与苯肾上腺素改善法乐氏四联症病人S_pO_2的临床观察
- Author:
Weiping CHENG
- Publication Type:Journal Article
- Keywords:
Nitric oxide;
Tetralogy of Fallot;
Phenylephrine;
Heart surgery
- From:
Chinese Journal of Anesthesiology
1994;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: This study was to evaluate the effects of inhalation of nitric oxide combined with intravenous phenylephrine on the arterial hypoxemia and tissues acidosis in patient with tetralogy of Fallot. Method: The 34 pa tients were randomly divided into Ⅰ(n=17) and Ⅱ(n=17) groups. In both groups, when the patient's SpO_2 was less than 80%, the intervention began. In Ⅰ group,a bolus dose(1?g/kg) of phenylephrine was given intermittently, until the SpO_2 was large than 90% or blood pressure increased to 120%, of baseline. In Ⅱ group, inhalation of 20 ppm NC was combined with intermittent bolus of phenylephrine 1?g/kg. Result: The value of SpO_2, MAP and BE had no sig nificant differences between two groups at pre-treatment. In Ⅱ group, SpO_2 was higher, meanwhile MAP, the negative value of BE,the total dose of phenylephrine used were lower than those in Ⅰ group after treatment (P
