Change of plasma nitric oxide and lactate concentrations in patients with hemorrhagic shock
- VernacularTitle:失血性休克病人血中一氧化氮和乳酸浓度的变化
- Author:
Junke WANG
;
Ling PEI
;
Guozhong XU
- Publication Type:Journal Article
- Keywords:
Nitric Oxide Shock, hemorrhagic Lactate
- From:
Chinese Journal of Anesthesiology
1994;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the relationship between the plasma concentration of nitric oxide (NO) and prognosis of the hemorrhagic shock. Method:The blood levels of NO and Lactate (LA) were measured with fluorophotometry and colorimetry in 30 hemorrhagic shock patients,and another 30 patients for elective surgery served as a control. Result :Concentration of NO was significantly lower and that of LA was significantly higher in hemorrhagic shock group than that of control group. NO level had a negative correlation with LA level and injury index. NO level in the patients complicated by sepsis were still lower than the control. Conclusion:Decrease of NO level may result in disturbance of microcirculation and increase of LA. So nitroglycerin should be used as early as possible in the hemorrhagic shock patients.
