Correlation analysis of bispectral index,spectral edge frequency of electroencephalogram with midazolam-induced sedation
- VernacularTitle:脑电图双频谱指数、边缘频率与咪唑安定镇静作用的相关性研究
- Author:
Jichang LI
;
Xinliang ZHUANG
;
Ning KONG
- Publication Type:Journal Article
- Keywords:
Midazolam Conscious sedation Electroencephalography Bispectral index Spectral edge frequency
- From:
Chinese Journal of Anesthesiology
1994;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To analyse correlation of bispectral index,spectral edge frequency of electroencephalogram with midazolam-induced sedation. Method: 30ASA grade Ⅰ-Ⅱ adult patients, undergoing elective surgery under regional anesthesia were randomly devided into three groups according to intravenous bolus doses of midazolam,i, e. group Ⅰ:0.05mg?kg~(-1),group Ⅱ:0.1mg?kg~(-1),group Ⅲ:0.2mg?kg~(-1). After an intravenous bolus dose of mida zolam was administered,both bispectral index (BIS), 95% spectral edge freguency (SEF) of electroencephalogram were monitored and their correlation with midazolam induced sedation was analysed. Result: Both BIS and 95% SEF-correlated with midazolam-induced sedation significantly (r= 0.86,0.73, P
