Experimental study of changes of intestinal immunity following traumatic shock and resuscitation
- VernacularTitle:创伤性休克及复苏后肠粘膜免疫功能的改变
- Author:
Xia LIU
;
Huifang XU
;
Wei JIANG
- Publication Type:Journal Article
- Keywords:
Intestines Immunity Endotoxins Resuscitation Shock, traumatic
- From:
Chinese Journal of Anesthesiology
1994;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: We investigated experimentally the changes of intestinal immunity following shock and resuscitation after trauma. Method:The experimental model was made in rats, which underwent laparotomy, then bleeding and reinfusing through the right fetmoral artery. Result: The concentration of IgA following shock and resuscitation were significantly higher than that before shock.. The concentration of IgA 24 h following resuscitation was the lowest, and was significantly lower than that at the end of shock.. The endotoxin in portal vein following shock and resuscitation were higher than that before shock.. The endotoxin level 24 h following resuscitation was the highest, and markedly higher than that at the end of shock. Conclusion: The traumatic shock and resuscitation are capable of causing intestinal immunosuppression and endotoxemia.
