Study of the Type of Infiltrating T Cells in Allergic Contact Dermatitis
- VernacularTitle:过敏性接触性皮炎反应中浸润T细胞类型研究
- Author:
Yalai BAI
;
Chunlei ZHANG
;
Lingfang ZENG
- Publication Type:Journal Article
- Keywords:
Dermatitis;
contact;
Interleukin-2;
Interferon ?
- From:
Chinese Journal of Dermatology
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
In order to investigate the type of infiltrating T cells in allergic contact dermatitis (ACD) reaction, by the methods of RT-PCR and immunohistochemistry, we tried to detect IL-2mRNA, IL-2, IFN-?, IL-4 in the lesions of patients with ACD. The results showed that Th1 cytokines were expressed aberrantly in ACD patients and Th1-like clone which secrets IL-2, IFN-? appeared to be predominant in ACD reaction.