Polysaccharidical peptides augmented the functions of tumour infiltrating lymphocytes
- VernacularTitle:云芝糖肽对肿瘤浸润淋巴细胞功能的促进作用
- Author:
Min ZHOU
;
Zhihan JIAN
- Publication Type:Journal Article
- Keywords:
Polysaccharides ? Neoplasms ? Lymphocytes
- From:
Chinese Journal of Pathophysiology
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The effects of polysaccharidical peptides (PSP) on the functions of tumour infiltrating lymphocytes (TILs) in vitro was explored. The results showed that PSP, at the concentration of 37-1200?g/ml, promoted the proliferation of TILs in dose-related manner. Combination of PSP with interleukin-2 (IL-2) enhanced the cytotoxicity of TILs and reduced the dose of IL-2 used for activating TILs. The results suggested that PSP could augment the proliferation and cytotoxicity of TILs in vitro.
