Study of the Effects of Melagenine on Melanocyte Proliferation and Malanin Synthesis
- VernacularTitle:黑素生成素对黑素细胞增殖和黑素合成作用的研究
- Author:
Aie XU
;
Xiaodong WEI
;
Zhigang BI
- Publication Type:Journal Article
- Keywords:
Melagenine;
Melanocyte;
Melanin;
Vitiligo
- From:
Chinese Journal of Dermatology
1995;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Cao reported that melagenine extracted from human placenta was effective in the clinical treatment of vitiligo, to elucidate the possible mechanism involved, melagenine and placenta peptide were added to melanocytes in the culture, and the culture without melagenine as control. The results obtained by MTT showed that melagenine can stimulate melanoeyte proliferation, its promoting rate was 42.5%, while placenta peptide got a promoting rate of 5.9%, the difference was significant (P
