Myocardial protective effects of continuous infusion with normothermic oxygenated crystalloid solution or blood cardioplegia during normothermic cardtopulmonary bypass
- VernacularTitle:常温体外循环下常温充氧晶体和氧合血停搏液持续灌注的心肌保护效果
- Author:
Hong GAO
;
Zhihao YU
;
Tian YU
- Publication Type:Journal Article
- Keywords:
Cardioplegic solution Cardiopulmonary bypass Myocardial protection Normothermia Hypothermia, induced
- From:
Chinese Journal of Anesthesiology
1995;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
The myocardial protective effect of continuous infusion with normothermic oxygenated crystalloid solution or blood cardioplegia during normothermic CPB was studied in 15 dogs. Ultrastructure. levels of adenine nucleotides,lipid peroxide (LPO),water content of heart musle,hemodynamics were observed. Dogs were randomly divided into three groups. Group Ⅰ: intermittent infusion with cold crystsalloid cardioplegia during hypothermic CPB (n=5); Group Ⅱ: continuous infusion with normothermic oxygenated blood cardioplegia during normothermic CPB(n=5); Group Ⅲ: continuous infusion with normothermic oxygenatde crystalloid cardioplegia duriug normothermic CPB((n=5). The normal mitochandria contents and glycogen stores in group Ⅱ and Ⅲ were significantly higher than those in group Ⅰ(P
