Changes of power of cerebral topographic map and electroencephalogram during anesthesia induction with propofoi,sodium thiopental or gama hydroxybutyrate sodium
- VernacularTitle:异丙酚、硫喷妥钠和羟丁酸钠麻醉诱导中脑电图及脑地形图功率变化的观察
- Author:
Shuzhen ZHANG
;
Enzhen WANG
;
Yuling TAN
- Publication Type:Journal Article
- Keywords:
Propofol Gama hydroxybutyrate sodium Sodium thiopental Cerebral topographic map Electroencephalogram
- From:
Chinese Journal of Anesthesiology
1994;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Cerebral topographic map (CTM) and electroencephalogram (EEG) can evaluate the functional activity of brain, and the purpose of this study was to objectively compare the effect of intravenous anesthetics on brain. Forty-five patients, ASA grade Ⅰ-Ⅱ, undergoing neurosurgery,were randomly divided into three groups after administration of Innovar 2 ml, and then equivalent effective dose of propofol(2～2.5 mg/kg)(Ⅰ),sodium thiopental (4～6mg/kg)(Ⅰ) or gama hydroxybutyrate sodium (70～80mg/kg)(Ⅲ) was intravenously given respectively. All patients were monitored continuously during induction. The high frequent excitative activities of ? rhythm appeared immediately after each anesthestic was injected. During the most effective period: in group Ⅰ, there were no ? rhythm in EEG and obvious power change on CTM; in group Ⅱ irregular ? rhythm took place in EEG occasionally and great increase in top power on CTM occured, which showed evident elevation compared with group Ⅰ (P
