Identification of Vitiligo Antigens
- VernacularTitle:白癜风抗原的辨认
- Author:
Zhong XIE
;
Suzhen JI
;
Liyu SHEN
- Publication Type:Journal Article
- Keywords:
Vitiligo;
Antigens;
melanocytes;
Melanocytes
- From:
Chinese Journal of Dermatology
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
It is known that patients with vitiligo often have antibodies to melanocytes. In order to identify vitiligo antibodies react to corresponding antigens, we used cultured normal human melanocytes to react with sera from 48 patients with vitiligo, the result showed that 52% of patients with vitiligo have antibodies to cell-surface antigens of melanocytes. Then immunoprecipitation and SDS-PAGE analysis were used to reveal molecular weights (MW) of the antigens, the result showed that the MW are about 75 000, 90 000, 110 000, and 150 000.
