Expression of Proliferating Cell Nuclear Antigen in Squamous Cell Carcinoma of the Skin
- VernacularTitle:增殖细胞核抗原在皮肤鳞癌中的表达
- Author:
Jianli WANG
;
Li CHEN
- Publication Type:Journal Article
- Keywords:
Carcinoma,squamous cell;
Antigen, proliferating cell nuclear
- From:
Chinese Journal of Dermatology
1994;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The expression of proliferating cell nuclear antigen (PCNA) was studied in 50 cases of squamous cell carcinoma of the skin using immunohistochemistry and PCNA cyclin monoclonal antibody. PCNA staining was found in the nuclei of tumour cells, two types of staining were seen, a granular pattern and a more diffuse nuclear staining. The expression of PCNA showed a significant positive correlation with degrees of differentiation of the carcinoma cells and lymph node metastasis (P
