Influences of lactic acidosis and pH on pulmonary vasoconstriction and gas exchanges in dogs.
- VernacularTitle:乳酸中毒和pH对狗肺血管张力和气体交换功能影响的实验研究
- Author:
Yuguang HUANG
;
Hongxuan YE
;
Wong KC
- Publication Type:Journal Article
- Keywords:
Metabolic;
acidosis;
Lactic acid Hydr-ochloric acid Pulmonary vasoconstriction
- From:
Chinese Journal of Anesthesiology
1994;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
The influences of lactic/hydrochloric acidosis on pulmonary vasoconstriction and gas exchanges were investigated in 36 dogs. The tv infusion of lactic or hydrochloric acid reducing arterial pH to 7. 00 could elicit significant changes of pulmonary hemodynamics, including the consistent increase of pulmonary arterial pressure and the decrease of arterial oxygen saturation. It is suggested that pulmonary vasocostriction is related to arterial PH but not to arterial lactic acid levels.