GENETIC POLYMORPHISM OF C_1R SUBCOMPONENT OF THE FIRST COMPLEMENT COMPONENT IN CHINESE POPULATION
- VernacularTitle:中国人群补体C_1R的遗传多态性
- Author:
Jian TIE
;
Xiuling WANG
;
Jingtao JIA
- Publication Type:Journal Article
- Keywords:
C_1R Polymorphism Chinese population
- From:
Chinese Journal of Forensic Medicine
1987;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Genetic polymorphism of the C1R subcomponent of human first complement component was in-vestigated in 360 unrelated Chinese individuals using isoelectric focusing followed by immunoblotting.Six common and four rare were detected. The allele frequencies were as follows: C1R * 1 = 0. 5181,C1R ? 2=0. 5291,C1R * 3= 0. 1472 and C1R * R(C1R * 5,C1R * 6,C1R * 12 and C1R * 13) = 0.0056. The distribution of allotypes fitted the Hardy-Weinberg equilibrium. This complemlement sys-tem is a useful genetic marker for anthropological studies and forensic science practice.
