Inhibitory effects of salviae miltiorrhizae and SOD on lipid Peroxidation after hemorrhagic shock.
- VernacularTitle:失血性休克中丹参和超氧化物歧化酶抑制脂质过氧化反应的研究
- Author:
Zhenyuan XIA
;
Jinfu YU
;
Xinyun SHI
- Publication Type:Journal Article
- Keywords:
Hemorrhagic shock Lipid peroxidation
- From:
Chinese Journal of Anesthesiology
1994;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Effects of salviae miltiorrhizae (SM) and SOD on serum and tissue (liver, intestine) lipid peroxidation were studied on rabbits in reperfusion after hemor rhage shock.The results showed that both SM and SOD could effectively reduce the serum MDA,while the inhibitory effect of SM on tissue (intestine) lipid Peroxidation was more significant than that of SOD.90 min after shock,18 rabbits were equally divided into 3 groups,one third of shed blood was re-infused and simultaneously teperfused with balanced salt solution (BSS) (group A), SOD in BSS (group B) and SM in BSS (group C). After reperfusion, serum MDA increased significantly in group A, while serum in MDA in group B and C decreased gradually and was significantly lower than that of group A after reperfusion of 3 hr (I3). Intestine MDA in group C was evidently lower than that in group A (P
