?-Glutamyl transpeptidase activity and GSH content in benign hyperplastic prostatic tissue and stroma and epithelial cells
- VernacularTitle:良性增生前列腺组织及上皮和间质细胞中?-GT活性及GSH含量研究
- Author:
Xianxi LIU
;
Yuqin LIN
- Publication Type:Journal Article
- Keywords:
Glutathion;
Prostatic diseases;
Prostate;
Men
- From:
Chinese Journal of Pathophysiology
1989;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
?-GT activity and its substrate GSH content in tissue homogenate, epithe-lium and stroma of normal and benign hyperplastic human prostates were measured tostudy their relationship with pathogenesis of benign prostatic hyperplasia (BPH). Theresults were: a) ?-GT activity in BPH tissues were very much increased; but GSHcontent was much decreased; b) The ?-GT activity in epithelium of both normal andBPH were much higher than that in relative stroma. However epithelium GSH contentwere lower than that of stroma. Thase results suggested that increand ?-GT activity anddecreased GSH content play an important role in pathogenesis of BPH.
