Effect of vasectomy on testosterone receptor in rabbit prostate
- VernacularTitle:输精管结扎对兔前列腺睾酮受体的影响
- Author:
Yang LI
;
Zhongshan WANG
- Publication Type:Journal Article
- Keywords:
Deferens;
Ligation;
Prostate;
Testosterone;
Receptor
- From:
Chinese Journal of Pathophysiology
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
14 Japanese white male rabbits were used in this experiment, 7 of themwere sham operation group (SOG), 7 were vasectomized group (VG). The changes of testo-sterone receptor in prostate and serum testosterone were measured 16 months after vasec-tomy. The results showed that the Kd values in cytosol in VG and SOG were 10.21 nMand 3.42 nM and the Bmax were 33.68 and 10.42 fmol/mgpro. respectively; the Kd va-lues in nucleus were 9.36 and 4.81 nM and Bmax were 440.90 and 203.66 fmol/mg DNArespectively. By single point analysis, the cytosolic testosterone receptor concentrationswere found to be 26.13?5.64 and 8.40?1.66 fmol/mgpro. respectively, being significan-tly higher in VG as compared with SOG (P
