Hemorheologic changes during acute lung injury induced by oleic acid on dogs
- VernacularTitle:家犬油酸性急性肺损伤时的血液流变学变化
- Author:
Xizhong CUI
;
Longshao XU
- Publication Type:Journal Article
- Keywords:
Lung;
Oleic acids;
Erythrocyte aggregation;
Magnesium;
Fibrin fibrinogen degradation products
- From:
Chinese Journal of Pathophysiology
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Erythrocyte aggregation and related parameters were observed in this study.Erythrocyte aggregation index, hematocrit and fibrin fibrinogen degradation products in-creased significantly at 5 minutes after oleic acid injection. Erythrocyte electrophoretic timein native plasma delayed obviously at 5 minutes after oleic acid injection, whereas that inPBS altered very little. The concentration of plasma calcium and erythrocyte intracellularmagnesium decreased at 5 minutes, while plasma magnesium increased. The stepwise reg-ression analysis suggested that during lung injury the parameters that have greatest effect onerythrocyte aggregation were the change of hematocrit, erythrocyte intracellular magnesiumand negative charge of erythrocyte surface.
