Effect of biliary hypertension on cardiovascular activity in rabbits
- VernacularTitle:胆道加压时家兔心血管活动的变化
- Author:
Qichang ZHENG
;
Jianyu YE
- Publication Type:Journal Article
- Keywords:
Biliary tract;
Pressure;
Blood pressure;
Cardiovascular system;
Cholangitis
- From:
Chinese Journal of Pathophysiology
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
In order to study the effect of acute biliary hypertension on cardiovascu-lar activity, an experiment has been done on Japanese big ear white rabbits, using a self-made catheter with an inflatable rubber bag fixed to its anterior end. It was insertedinto the extrahepatic biliary tract via the duodenum, biliary high pressure of 8-20 kPawas created and maintained for 2 h by inflating the bag with water. A significant decreaseof cardiac output (CO) and fall of the arterial blood pressure were found during theexperiment (P0.05). These results indicated that the increase ofthe biliary pressure without infection could also make CO decrease, so it was a direct rea-son for falling of blood pressure, it was also an important factor causing the decline ofblood pressure in the ealier stage of severe acute cholangitis (ACST).
