The calcium antagonism of radix salviae miltirrhiziae (RSM) in antihepatocellular necrosis
- VernacularTitle:丹参在抗肝细胞坏死中的钙拮抗作用
- Author:
Lingzhi ZHANG
;
Yuanchang ZHAO
- Publication Type:Journal Article
- Keywords:
Live;
Calcium;
Calcium channel blocker
- From:
Chinese Journal of Pathophysiology
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
In this study, carbontetrachloride was administered orally to male Wistarrats at a dose of 2.5ml/kg body weight. The protective effects of RSM were comparedwith that of verapamil (a well-known calcium antagonist), and regitine (a vasodilator),to study the mechanisms of RSM action. The results showed that a significant correlation between CCl_4-induced liver tissuenecrosis and liver tissue calcium content(r=0.887, P
