Effects of drinking tea on hemodynamics and acute hypoxic pulmonary hypertension in dogs——role of prostaglandins
- VernacularTitle:饮茶对狗急性低氧性肺动脉高压的影响——前列腺素的作用
- Author:
Chuanyi LU
;
Dixun WANG
- Publication Type:Journal Article
- Keywords:
Tea;
Anoxia;
Lung;
Pulmonary artery;
Dogs
- From:
Chinese Journal of Pathophysiology
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The effects of acute intragastric administration of tea on hemodynamicsand acute hypoxic pulmonary hypertension were studied by a catheterization technique inspontaneously breathing dogs. The tea was made by adding 25g tea to 400ml boiling wa-ter and was given to each dog in a dosage of 20ml/kg. Both greentea and black-tea didnot affect the hemodynamics obviously. However hypoxic pulmonary vasoconstriction wasinhibited significantly by black-tea. The increase in the plasma concentration of TXA_2induced by acute exposure to hypoxia was also inhibited by black-tea. Green-tea did notshow any effect on HPV and plasma level of TXA_2 and 6-keto-PGF_1??The findings thatblack-tea can reduce the magnitude of HPV may have therapeutic significance in the pre-vention and cure of pulmonary hypertension, pulmonary heart disease and high altitudeheart disease.
