Effect of agkistrodon antithrombotic enzymes (Svate) on renal microcirculatory perfusion in hemorrhagic shock animals
- VernacularTitle:蝮蛇抗栓酶对失血性休克动物肾微循环血液灌流量的影响
- Author:
Hongxi XU
;
Yunping XI
- Publication Type:Journal Article
- Keywords:
Shock,hemorrhagic;
Kidney;
Microcirculation;
Perfusion
- From:
Chinese Journal of Pathophysiology
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
The microcirculatory perfusion of liver, spleen, kidney, small intestine andtail were measured by a laser doppler flowmeter after intravenous injection of agkistro-don antithrombotic anzyme (0. 05 U, 0. 025 U/100 g B. W.) in 40 hemorrhagic shockrats and 15 hemorrhagic rabbits. The results showed that 5～20 min after injection therenal perfusion increased significantly, but there was no marked increase of renal arteryblood flow when it was simultanously detected with a electromagnetic flowmeter, thoughthe urine was increased. Authors suggested that Svate may have decreased the resistenceof renal microcirculation and accelerate the veosity of renal microcirculation, thus theyincreased the microcirculatory perfusion in renal cortex.
