Free radical reaction and erythrocyte membrane damage in disseminated intravascular coagulation (DIC) caused by endotoxin
- VernacularTitle:家兔内毒素性DIC病理过程中的自由基反应与红细胞膜损伤
- Author:
Jienan AO
;
Zhenkun QIAN
- Publication Type:Journal Article
- Keywords:
Disseminated intravascular coagulation;
Free radicals;
Lipid peroxides;
Superoxide dismutase;
Membrane fluidity
- From:
Chinese Journal of Pathophysiology
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
The effect of free radicals and the mechanism of cell damage in the patho-logical process of endotoxin DIC was studied to elucidate the relationship between freeradicals reaction and erythrocyte membrane injury in DIC induced by endotoxin. Molecu-lar biomechanics, biomembrane chemistry were applied to rabbits in this work. Resultsshowed that there was a significant increase both in RBC membrane lipid peroxides level(0. 285?0. 063, P
