The Effects of Technicolosixal Precesses on the dissolubility of Enteric Coating Aspirin Tablets
- VernacularTitle:阿斯匹林肠溶片的不同工艺对其溶出度影响考察
- Author:
Hengshan TAN
;
Xiaoning LIU
;
Shang ZHONG
- Publication Type:Journal Article
- Keywords:
enteric coating aspirin tablets dissolubility parameter for release
- From:
China Pharmacy
1991;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
The effects of different technicological processes on the dissolubility of enteric coating aspirin tablets were studied. With testing in vitro, significant differences were found among three kinds of tablets from four factories in dissoluble feature. The length of time needed for release and that for disintegration of tablets from Factory C were 90 minutes and 5 minutes repectively, which were the shortest,and those from Factocy B, 210 minutes and 120 minutes repectively,which were the longest among three kinds of tablets. The average dissoluble amount of aspirin contained in tablets from Factory C was 74.07％;Factory D,74. 51％; Factory A, 66.6％; and Factory B, 62.51％. All the parameters determined were statistically different among three kinds of products by analysis of varianee(p
