The study of cerebral ischemia caused by myocardial infarcion in rat
- VernacularTitle:大鼠心肌梗塞致脑缺血的研究
- Author:
Beiqi ZHANG
;
Ning MA
- Publication Type:Journal Article
- Keywords:
Myocardial infarction;
Cerebral ischemia;
Malondialdehyde
- From:
Chinese Journal of Pathophysiology
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Developing changes of physiology and biochemistry in myocardium and brain tissue after myocardial infarction in rats was observed. The result showed that BP、 ?dp/dtmax and BBF were dccreased significantly at 6 hours after ischemia. The BBF was returned to normal after 72 hours but BP and ?dp/dtmax wcrc kept lower for 7 days. The MDA was clearly higher at 72 hours and returned to normal at 7th days in myocardium and brain tissue. BUt the NAGase reached to the peak at 7th days and was returncd to normal at 14th days. The changes of MDA and NAGase were correlated to the changes of heart fuetion after myocardial infarction. It suggested that cardiogcnic cerebral ischemia is a real fact.
