The febrifugal effect and analysis on its mechanism of electric needling "Shang gen" point after sectioning infraorbital nerves of rabbits with fever
- VernacularTitle:离断家兔双侧眶下神经对电针“山根穴”降热效应及脑脊液cAMP含量变化的影响
- Author:
Ziqiang LIU
;
Chenglong SHI
- Publication Type:Journal Article
- Keywords:
Fever;
Pyrogen;
Adenosine cyclic monophosphate
- From:
Chinese Journal of Pathophysiology
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
In order to observe the febrffugal response and analysis on its mechanism of needling "Shang gen" point bilateral infraorbital nerves of rabbits were sected in the experiment. Fever models were made by leukocytic pyrogen. The experiment findings were as follows:1. It was found that when febrile response of leukocytic pyrogen in rabbits was significant, the cAMP content in CSF was strikingly increase (25.14?2.11pmol/L). During electric needling "Shang gen" point of febrile rabbits, however, fever response was markedly inhibited (△T was 0.27?0.07 at 60min); The cAMP content rise in CSF was markedly inhibited (11.22?0.13 pmol/ml).2. After sectioning bilateral infraorbital nerves of rabbits, the fever response of febrile rabbits was not depressed (△T was 0.71?0.06 at 60min) during electric needling "Shang gen" point. In the mean time, the cAMP content in CSF was significantly increased (28.53?1.12 pmol/ml).3. The authors inferred that the mechanism of febrffugal response of electric needling "Shang gen" point might be closely associated with producing nerves impulse (from the that point) which inhibited probablely the synthesis of cAMP through some modes.