Changes of cyclic AMP and adenylate cyclase in different areas of rat brain during fever induced by endotoxin
- VernacularTitle:大鼠内毒素性发热时不同脑区cAMP含量和腺苷酸环化酶活性的变化
- Author:
Dejun XING
;
Kuiqin DU
- Publication Type:Journal Article
- Keywords:
Endotoxin;
Fever;
Cyclic AMP;
Adenylate cyclase
- From:
Chinese Journal of Pathophysiology
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The fever was induced by intraperitoneal injecting of refined E.Coli endotoxin(ET). The cAMP level and the activity of adenylate cyclase (AC) in differen brain areas of rat were assayed.Both cAMP and AC in hypothalamus were increased significantly at the peak of fever in comparing with the control group (P