Pathogenesis of lung edema induced by oleic acid
- VernacularTitle:油酸引起肺水肿的机制探讨
- Author:
Zhengyan LUO
;
Dekun SONG
- Publication Type:Journal Article
- Keywords:
Lung;
Oleic acids;
xanthine oxidase;
Free radicals
- From:
Chinese Journal of Pathophysiology
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Three lines of studies (lung in sito, isolated perfused lung and cultured pulmonary artery endothelial cell, PAEC) were undertaken in our laboratory in recent years which demonstrated that oxygen free radicals (OFRs) participates in the pathogenesis of rat lung edema induced by oleic acid (OA). The OFRs derived from xanthine/xanthine oxidase in PAEC might play a primary and initial role, whereas that derived from PMNs might act as an important but secondary and amplifying role in the pathogenesis of lung edema induced by OA.
