Study of mechanism of alteration in hypoxic pulmonary vasoconstriction during hypothermia
- VernacularTitle:低体温时缺氧性肺血管收缩反应变化及其机制研究
- Author:
Ming FAN
;
Dixun WANG
- Publication Type:Journal Article
- Keywords:
Anoxia;
Vasoconstriction;
Sympathicus;
5-HT;
Prostaglandins
- From:
Chinese Journal of Pathophysiology
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
In order to clear up the mechanism of changes in hypoxic pulmonary vasoconstriction(HPV) during hypothermia, arterial plasma concentrations of norepinephrine, thromboxane B_2, 6-keto-PGF_(1?), 5-HT and 5-hydroxyindoleacetic acid(5-HIAA) were measured before and after hypothermia. The results showed that during acute alveolar hypoxia HPV enhanced significantly in hypothermic dogs, the percentage change of PVR increased from baseline 34.7?5.80% to 57.6?6.8% (P
