Effect of ahalysantinfarctasum on acute alveolar hypoxic pulmonary hypertension
- VernacularTitle:蝮蛇抗栓酶对狗急性肺泡缺氧性肺动脉高压的影响
- Author:
Aiping ZOU
;
Shangbin YU
- Publication Type:Journal Article
- Keywords:
Pulmonary artery;
Hypoxia;
Prostaglandin
- From:
Chinese Journal of Pathophysiology
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
The effect of ahalysantinfarctasum (AFT) on acute hypoxic pulmonary hypertension of dogs was examined. The'decrease in pulmonary vascular resistance and a dose dependent attenuation of acute hypoxic pulmonary vasoconstriction by AFT were found. AFT did not alter systemic vascular resistance. PaO_2 and PaCO_2 6-keto-PGF_(1?) increased significantly, however after the intravenous infusion of AFT, TXB_2 did not change. It is suggested that AFT may attenuate hypoxic pulmonary vasoconstriction by tnducing the synthesis or release of PG I to nreyent nulmonary hypertension
