Experimental Studies of Inducing Malignant Lung Tumor on Wistar Rats by Artificial Synthetic Tin Mine Dust
- VernacularTitle:人工合成矿尘诱发Wistar大鼠呼吸道肿瘤实验研究
- Author:
Run HUANG
- Publication Type:Journal Article
- Keywords:
Artifical synthetic mine dust;
Respiratory malignant tumor;
Tumor-inducing experiment
- From:
Journal of Kunming Medical University
1986;0(04):-
- CountryChina
- Language:Chinese
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Abstract:
There is a high incidence of malignant lung tumor in Yunnan tin mine area.In order to detect the causes,the mixtures of artificial synthetic mine dust containing As,Pb,Fe etc(No. 1,2,3)were used for tumor-inducing experiments on Wistar rats.The results were as follows: 31 lung sarcomas were developed in 3 experimental groups and the incidence was 22.6%.The malignant lung lymphomas developed in 28 of 31 sarcomas,the rate being 90.2%.In addition, 3 cases of lung cancer were found.No benign or malignant lung tumor was found in the con- trol group.The results showed that the artificial synthetic mine dust(No.1,2,3)was related to the lung sarcoma formation on Wistar rats,which is reported for the first time.
