The effect of hyperestrogenemia on myocardial contractility and relaxation in myocardial infarction observed in female rats
- VernacularTitle:高雌激素血症对雌性心肌梗塞大鼠心肌舒缩性能的影响
- Author:
Wannian ZHANG
;
Zhiping LIU
- Publication Type:Journal Article
- Keywords:
Estradiol;
Female;
Rats;
Myocardial infarction;
Myocardial contraction
- From:
Chinese Journal of Pathophysiology
1989;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
The effect of hyperestrogenemia induced by intramuscular injectied estradiol (E_2) on myocardial contractility and relaxation was observed in female rats with myocardial infarction (MI). The results showed that: (1) In MI group, the plasma estradiol level increased slyghtly and then droped, while the level of estradiol increased markedly in rats treated by E_2 in MI (MIE_2) group. (2) Diameter of myofibril in MIE_2 grows more than that of control sham operation(CS) and MI (10.65?0.59 VS 7.65?0.40 and 10.15?0.54?m, P
