Effects of cigarette smoking on hypoxic pulmonary vasoconstriction in piglets—role of sympathetic nerve, histamine,prostaglandins and leukotrienes
- VernacularTitle:吸烟对幼猪急性缺氧引起的肺血管收缩反应的影响—儿茶酚胺、组胺、前列腺素及白三烯的作用
- Author:
Weihan WANG
;
Dixun WANG
- Publication Type:Journal Article
- Keywords:
Anoxia;
Histamine;
Leukotrienes;
Prostaglandins;
Smoking;
Sympathetic nerves system;
Pulmonary artery
- From:
Chinese Journal of Pathophysiology
1989;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
In order to investigate the effects of cigarette smoking on hypoxic pulmonary vasoconstriction(HPV) in piglets, receptor or synthetic enzyme blockers of sympathetic nerve, histamine, prostaglandins(PGs) and leukotrienes(LTs) were used. Results showed that hypoxia increased PVR by adrenergic alpha receptor, LTs and PGs to 72.5%(3min. P
