Protective effect of DS-182 on the H~+-ATPase activity of rat myocardial mitochondria against free radical damage
- VernacularTitle:丹参素对氧自由基所致大鼠心肌线粒体H~+-ATP酶损伤的保护作用
- Author:
Yinzi CHANG
;
Dianquan LIANG
- Publication Type:Journal Article
- Keywords:
Myocardium;
Mitochondria;
Free radicals;
H~+-Transporting ATPase
- From:
Chinese Journal of Pathophysiology
1989;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Mitochondria isolated from rat heart was used to study the protective effect of DS-182 against free radical damage, which was resulted from FeSO_4/Ascorbic acid. It was found that free radicals decreased the H~+-ATPase activity of mitochondria significantly, however, DS-182 inhibited this anti H~+-ATPase activity induced by free radicals (P
