Studies on the prolactin receptors on the membrane of rat liver cells
- VernacularTitle:大鼠肝细胞泌乳素受体的研究
- Author:
Mengyuan LIU
;
Su ZHOU
- Publication Type:Journal Article
- Keywords:
Prolactin;
Receptors;
Liver
- From:
Chinese Journal of Pathophysiology
1989;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Binding sites or receptors for prolactin were identified in crude membrane fractions prepared from female lactating Sprague-Dawley rat using receptor radioassay. The results further indicated that the membrane of rat liver cells are rich in prolactin receptors, and the Scatchard analysis of the binding of ~(125)I-oPRL to receptors revealed that female rat liver cells contained two classes of prolactin receptors (Kd_1=3.20?10~(-10) M, Kd_2=1.26?10~(-8)M) with high specificity.
