Effect of GPM on Hippocampal DND Following Transient Brain Ischemia in Gerbils
- VernacularTitle:绞股蓝总皂甙对沙土鼠短暂性脑缺血后海马DND的影响
- Author:
Changqing XU
- Publication Type:Journal Article
- Keywords:
GPM;
Transient brain ischemia;
DND;
Gerbil
- From:
Journal of Kunming Medical University
1988;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Hippocampal delayed neuronal death(DND)model was produced by bilateral carotid arteries occluded for 10 min with 7 day reperfusion.Effect of GPM on DND of gerbil hippocampus was examined by counting the neuronal density and histologic changes in CA_1sector.The average neuronal density((?)?SD)in NS group.GPM-I,GPM-Ⅱ group was 107.50?6.63/mu,146.18?19.75/mm and 165.30?9.24/mm respectively.Compared with NS contral group,both neuronal density in GPM-I group and GPM-Ⅱ group were significantly increased(P