The relation between liver low density lipoprotein (LDL) receptor activity and serum cholesterol levels in human fetus
- VernacularTitle:人胚肝低密度脂蛋白受体活性与血清胆固醇水平的关系
- Author:
Chonglun XIE
;
Haijiang CAI
- Publication Type:Journal Article
- Keywords:
Lipoproteins, LDL;
Cholesterol;
Fetus
- From:
Chinese Journal of Pathophysiology
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
The activity of the solubilized receptor was assayed by precipitating the receptor with acetone in the presnce of egg phosphatidyleholine liposomes. It was found that the binding of ~(125)I-LDL to fetal liver receptors rose significantly with the increase of fetal age. During the same period, the total cholesterol (TC) and LDL-eholesterol (LDL-C) levels in fetal serum declined progressively. The correlation between fetal age and concentration of TC and LDL-C were -0.80(P
