Thromboxane A_2 and prostacyclin and the development of hypertension in spontaneous hypertensive rats
- VernacularTitle:血栓素A_2和前列腺环素与自发性高血压大鼠高血压发展的关系
- Author:
Guoxiong YANG
;
Guozhong ZHANG
- Publication Type:Journal Article
- Keywords:
Thromboxane A_2;
Prostaglandins X;
Hypertension;
Rats
- From:
Chinese Journal of Pathophysiology
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
The change of plasma TXB_2 and 6-Keto-PGF_1? which were stable metabolites of TXA_2 and PGI_2 respectively were observed in arterial blood of SHR and WKY and in different ages of SHR. The 6-Keto/TXB_2 ratios were computed. The results showed that TXB2 concentration of arterial blood were significantly higher in SHR than in WKY(1217.9?298.5Pg/ml vs 207.1?59.8Pg/ml, P
