The effect of saponin isolated from stems and leaves of ginseng (SLG) on immunologic function in mice
- VernacularTitle:人参茎叶皂甙对小鼠免疫功能的影响
- Author:
Su MA
;
Beichen WANG
- Publication Type:Journal Article
- Keywords:
Ginseng;
Immunilogic function
- From:
Chinese Journal of Pathophysiology
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The effects of SLG on the immune function of normal and immune-suppressed mice were investigated. The results showed that SLG (50mg/kg, im) could correct the suppressive effect of cyclophosphamide, dexamethasone or prednisolone on spleen and. thymus weight, serum specific antibody level and lymphocyte transformation. SLG could also improve the phagocytic activity of peritoneal macrophages and enhance peripheral blood ANAE+-lymphocyte ratio of mice. No obvious effect of SLG on the normal mice were observed except that it could increase the antibody level of normal mice. The results implicate that SLG may have some immunomodulatory effect.
