Preliminary Study on the Mode of Inheritance of Male Pattern Alopecia (MPA)
- VernacularTitle:男性型秃发遗传方式的初步探讨
- Author:
Shuo DENG
- Publication Type:Journal Article
- Keywords:
Male pattern alopecia;
Inheritance;
Simple;
segrgeation analysis;
Hentability
- From:
Journal of Kunming Medical University
1988;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
95 probands' family frees of MPA have been studied by the methods of simple segregation analysis and estimation of heritability. The result shows that MPA may be caused by different hereditary patterns. In the families with affected parents and vertical transmission. MPA may be caused by an autosomal dominant (AD) gene, making up 56.84% (AD) and 2.11% (reduced penetrance). It also shows that MPA may be due to polygenic inheritance.