The effect of prostaglandin E_2 on the function and ultrastructure of cultured new born rat heart muscle cells
- VernacularTitle:前列腺素E_2对体外培养的新生大鼠心肌细胞的机能及超微结构的影响
- Author:
Shiying TAO
;
Guanbin DENG
- Publication Type:Journal Article
- Keywords:
Prostaglandins E;
Rats;
Myocardium;
Cells
- From:
Chinese Journal of Pathophysiology
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
PGE_2 reduced pulsation in concentration of 4 ng/ml and pause in 40 ng/ml for cultured rat heart muscle cells. Membrane and microfilament changes slightly in cultured heart muscle cells exposed to PGE_2 4 ng/ml for 6 min. But membrane presented marked distortion in cultured heart muscle cells exposed to PGE_2 4 ng/ml for 6 hr. These data indicated that effect of PGE_2 is time-dependent.
