Changes of central nervous system leucine-enkephaline in experimental hypo- and hyperthyroid rats
- VernacularTitle:大鼠实验性甲状腺功能低下或亢进情况下脑亮-脑啡肽含量的变化
- Author:
Jianguo LU
;
Baogang LIN
- Publication Type:Journal Article
- Keywords:
Hyperthyroidism;
Hypothyroidism;
Enkephalin, leucine
- From:
Chinese Journal of Pathophysiology
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
In presnt experiment, animal models for hyperthyroidism and hypothyroidism were made, and using radioimmunoassay, the immunoeactive leucine-enkephalin (Ir-LEK) levels of such discrete brain areas as hypothalamus, striatum, cerebral cortex(frontal lobe) and whole pituitary were determined in different groups. The results obtained indicated that both hyperthyroidism and hypothyroidism induced significant changes of concentration in CNS Ir-LEK. It was found in hypothyroid group that concentration of Ir-LEK in hypothalamus, cerebral cortex and pituitary increased significantly against the control (P
