Influence of low dose X-irradiation on enkephalin and endocrine hormone in male mice
- VernacularTitle:低剂量X线照射对小鼠脑啡肽和内分泌激素的影响
- Author:
Shouliang GONG
;
Weihong LIU
- Publication Type:Journal Article
- Keywords:
Radiation effect;
Enkephalin, methionine;
Enkephalin, leucine;
Testosterone;
Corticosterone;
Adenosine cyclic monophosphate
- From:
Chinese Journal of Pathophysiology
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
C_(57)BL/G male mice were immunized with SRBC 9 hr after 75 mGy whole body X-irradiation. The hypothalamic M-Enk and L-Enk contents were decreased. Serum TS level kept on fluctuating over the control level. The change of testicular cAMP content was not in the same direction as that of the TS. The change of serum CS level was opposite to that of serum TS, These results suggest that the low dose radiation probably cause the changes of neuroendocrine function, leading to the decrement of hypothalamic EOP contents, the supression of CRF-ACTH-CS axis activity and the enhancement of GnRH-LH-TS axis activity.
