Effect of Ca~(2+) concentration on the ventricular fibrillation threshold and its relation to the levels of cAMP, cGMP and ATP in rat ischemic heart
- VernacularTitle:钙离子浓度变化对大鼠缺血心室致颤阈值的影响及其与cAMP、cGMP及ATP的关系
- Author:
Chu CHEN
- Publication Type:Journal Article
- Keywords:
Ventricular fibrillation;
Calcium;
Adenosine cyclic monophosphate;
Guanosine cyclic monophosphate;
Adenosine triphosphate
- From:
Chinese Journal of Pathophysiology
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
The purpose of this study was to investigate the effects of different Ca~(2+) concentrations on the ventricular fibrillation threshold(VFT) in the acute reg- ional ischemic isolated, paced rat hearts and to investigate their relations to the levels of cAMP, cGMP and ATP in the myocardium. It was demonstrated that a positive correlation was observed between [Ca~(2+)] and the percentage of VFT lowered in the ischemic hearts (r=0.7998, P
