Effects of the traditional chinese medicine antiinflammation No. 6 on the production of prostaglandin E and lysozyme and expression of membrane C_(3b) receptors by rat peritoneal macrophages
- VernacularTitle:中药抗炎6号对大鼠腹腔巨噬细胞产生PGE、溶菌酶及C_3b受体表达的影响
- Author:
Yufei WANG
- Publication Type:Journal Article
- Keywords:
Macrophages;
Medicine, chinese traditional;
Prostaglandins;
Muramtdase;
Receptors, complement
- From:
Chinese Journal of Pathophysiology
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The traditional Chinese medicine Antiinflammation No6, composed of Flos Lonicerae, Herba Taraxaci, Folium Isatidis and Herba Houttuyniae and proved to be highly effective clinically in the treatment of certain acute bacterial and viral infections, has been found in the present study to inhibit the prostaglandin E productin by zymosan-stimulated rat peritoneal macrophages (RPM?). In contrast, the production of lysozyme by non-stimulated RPM?, as well as the expression of C_3b receptors on the macrophage plasma membrane, was markedly enhanced by the drug. All these results seem to be in accordance with the authors' speculation that the basic mechanisms underlying the clinical effect of the drug may well be due to, at least in part, its potentiating action on the immune system.
